Treatment of nonmelanotic hyperpigmentation with the Q-switched ruby laser
Identifieur interne : 002478 ( Main/Exploration ); précédent : 002477; suivant : 002479Treatment of nonmelanotic hyperpigmentation with the Q-switched ruby laser
Auteurs : Petra Maria Becker-Wegerich ; Annegret Kuhn ; Lucy Malek ; Percy Lehmann ; Mosaad Megahed ; Thomas RuzickaSource :
- Journal of the American Academy of Dermatology [ 0190-9622 ] ; 2000.
English descriptors
- Teeft :
- Acad, Acad dermatol, Antimalarial, Antimalarial agents, Complete disappearance, Cutaneous, Cutaneous lupus erythematosus, Dermatol, Dermatology, Dermis, Erythematosus, First patient, Fitzpatrick skin type, Herpesvirus sarcoma, Histologic findings, Hyperpigmentation, Laser, Laser applications, Laser systems, Laser therapy, Laser treatment, Lesion, Lupus, Melanin, Original magnification, Pigment deposits, Qsrl, Right forearm, Ruby, Ruby laser, Ruzicka, Sarcoma, Selective photothermolysis, Side effects, Significant improvement, Skin biopsy specimen, Skin lesions.
Abstract
Abstract: Hyperpigmentation of the skin is often refractory to conventional therapies, but has significant cosmetic implications if located on visible areas. Because laser systems are capable of removing pigment deposits caused by selective photothermolysis, we addressed the issue of whether the Q-switched ruby laser could be a useful alternative in the treatment of nonmelanotic hyperpigmented skin lesions. We report the successful treatment of a patient with hyperpigmentation caused by iatrogenic human herpesvirus 8–associated Kaposi’s sarcoma and a patient with hyperpigmentation caused by long-term antimalarial therapy for cutaneous lupus erythematosus. In both patients, clinical lightening of the darkly pigmented lesions was seen after a single treatment, and a significant improvement was observed after 3 laser applications. The patients tolerated the laser therapy well without any short-term side effects and did not experience either scarring or considerable textural skin changes. Histologic examination was performed before and after laser treatment to confirm the reduction of the pigment deposits. Our data indicate that treatment of nonmelanotic skin hyperpigmentation with the Q-switched ruby laser might be a safe and powerful therapeutic method. (J Am Acad Dermatol 2000;43:272-4.)
Url:
DOI: 10.1067/mjd.2000.105555
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Abstract: Hyperpigmentation of the skin is often refractory to conventional therapies, but has significant cosmetic implications if located on visible areas. Because laser systems are capable of removing pigment deposits caused by selective photothermolysis, we addressed the issue of whether the Q-switched ruby laser could be a useful alternative in the treatment of nonmelanotic hyperpigmented skin lesions. We report the successful treatment of a patient with hyperpigmentation caused by iatrogenic human herpesvirus 8–associated Kaposi’s sarcoma and a patient with hyperpigmentation caused by long-term antimalarial therapy for cutaneous lupus erythematosus. In both patients, clinical lightening of the darkly pigmented lesions was seen after a single treatment, and a significant improvement was observed after 3 laser applications. The patients tolerated the laser therapy well without any short-term side effects and did not experience either scarring or considerable textural skin changes. Histologic examination was performed before and after laser treatment to confirm the reduction of the pigment deposits. Our data indicate that treatment of nonmelanotic skin hyperpigmentation with the Q-switched ruby laser might be a safe and powerful therapeutic method. (J Am Acad Dermatol 2000;43:272-4.)</div>
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<tree><noCountry><name sortKey="Becker Wegerich, Petra Maria" sort="Becker Wegerich, Petra Maria" uniqKey="Becker Wegerich P" first="Petra Maria" last="Becker-Wegerich">Petra Maria Becker-Wegerich</name>
<name sortKey="Kuhn, Annegret" sort="Kuhn, Annegret" uniqKey="Kuhn A" first="Annegret" last="Kuhn">Annegret Kuhn</name>
<name sortKey="Lehmann, Percy" sort="Lehmann, Percy" uniqKey="Lehmann P" first="Percy" last="Lehmann">Percy Lehmann</name>
<name sortKey="Malek, Lucy" sort="Malek, Lucy" uniqKey="Malek L" first="Lucy" last="Malek">Lucy Malek</name>
<name sortKey="Megahed, Mosaad" sort="Megahed, Mosaad" uniqKey="Megahed M" first="Mosaad" last="Megahed">Mosaad Megahed</name>
<name sortKey="Ruzicka, Thomas" sort="Ruzicka, Thomas" uniqKey="Ruzicka T" first="Thomas" last="Ruzicka">Thomas Ruzicka</name>
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